Romans 1:7

To all that are in Rome. To all Christians in Rome. The letter is addressed to the church in the great imperial city. Rome was the capital of the world, the home of Nero, the emperor, the largest city on earth, supposed to contain about two million inhabitants.

Saints. All Christians were called saints by the New Testament writers. Any one consecrated to a holy life is a saint.

Grace to you and peace. This is the ordinary New Testament Christian salutation. It is the expression of a prayer that God the Father and our Lord may bestow favor and peace upon them. See 1Co 1:3 2Co 1:2 Ga 1:3 Eph 1:2 Col 1:2 1Th 1:1 2Th 1:2 Phm 1:3.

From God our Father, and the Lord Jesus Christ. The Father is the source, and our Lord Jesus Christ the mediator and procurer of these blessings. It is plain that Paul was not a Unitarian. Let it be noted that this section, written, as admitted by skeptical critics, less than thirty years after the crucifixion, by Paul, to a body of believers at a distance from Judea, affirms the main facts of the Gospels: (1) That Jesus was the Son of God. (2) That he took upon himself our nature. (3) That he displayed divine power. (4) That he was raised from the dead. (5) That men are saved by the obedience of the faith.
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